JERUSALEM—With President Donald Trump set to leave for the Middle East on Monday, talks between the U.S. and the Islamic Republic of Iran concluded a fourth round of negotiations in Oman on Sunday over Tehran’s illicit nuclear weapons program.
A day before the start of talks, Iranian Supreme Leader Ali Khamenei welcomed chants of “Death to America” in Tehran. “Your judgment is right,” Khamenei told a crowd of supporters who called for the destruction of the U.S.
Iranian Foreign Ministry spokesperson Esmail Baghaei said the nuclear talks were “difficult but useful.” A U.S. official, speaking on condition of anonymity to discuss the closed-door negotiations, offered a little bit more, describing them as being both indirect and direct, The Associated Press reported.
An “agreement was reached to move forward with the talks to continue working through technical elements,” the U.S. official said. “We are encouraged by today’s outcome and look forward to our next meeting, which will happen in the near future.”
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Iranian Supreme Leader Ali Khamenei attends Nowruz events in Tehran, Iran, on March 21, 2025. (Photo by Iranian Leader Press Office / Handout/Anadolu via Getty Images)
President Trump announced a 60-day time frame to reach an agreement with Iran over its illegal atomic weapons program. The first U.S. negotiating session with Iran commenced on April 12.
Mardo Soghom, an Iran analyst and journalist, noted prior to the start of talks several months ago that Iran’s regime will go to great lengths to preserve its right to enrich uranium—the material required for a nuclear weapon. The Trump administration vehemently opposes a uranium enrichment program on Iranian soil.
“Iran is trying to save its enrichment operation at a lower level and also not accepting any pressure to halt its anti-Israel stance. Khamenei’s speech [Saturday] highlighted that second point. But at this point, the main issue is dismantling Iran’s uranium enrichment,” Soghom told Fox News Digital.
Khamenei also lashed out at Israel during his Saturday speech in Tehran, declaring about Israel’s war campaign to root out Iran-backed Hamas terrorists from the Gaza Strip that “The people of Gaza are not facing Israel alone—they are facing America and Britain.”
Jason Brodsky, the policy director of United Against Nuclear Iran, told Fox News Digital that “The Iranians, like last round, sound more downcast than the U.S. side, describing talks as difficult.”
In 2018, President Trump withdrew from former President Barack Obama’s 2015 nuclear deal with Iran, known formally as the Joint Comprehensive Plan of Action (JCPOA), because the accord failed to prevent Tehran from building a nuclear weapons device, according to the first Trump administration.
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U.S. Special Envoy to the Middle East Steve Witkoff, left, shakes hands with Omani Foreign Minister Sayyid Badr Albusaidi in Muscat, Oman, April 12, 2025. (Oman News Agency/ Handout via Reuters)
President Trump’s Special Envoy to the Middle East Steve Witkoff recently stressed that Iran cannot have an enrichment program during an interview with Breitbart News prior to Sunday’s bargaining session.
Witkoff said “First of all, we’re never doing a JCPOA deal where sanctions come off and there’s no sunsetting of their obligations. That doesn’t make sense. That was a mismatched procedure in JCPOA. We believe that they cannot have enrichment, they cannot have centrifuges, they cannot have anything that allows them to build a weapon. We believe in all of that. That was not JCPOA. JCPOA had sunset provisions that burned off the obligations and burned off the sanctions relief at inappropriate times. It’s never going to happen in this deal.”
Brodsky said that “All in all, both sides want to keep the process moving. The Iranians will usually say and do enough to earn another meeting as they stand to lose more by this process breaking down than the U.S. government. The negotiating process is as important to the Iranians as the agreement itself as the process offers insulation from the impact of sanctions—with the rial strengthening since talks started—and protection from a military strike.
“This is why Iran will want these negotiations to continue for as long as possible. They will try to wear out and exhaust U.S. negotiators into concessions, which the Trump administration should reject. As President Trump said in a different context, Tehran does not have the cards here.”
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President Donald Trump arrives on Air Force One at Joint Base Andrews, Maryland, on Sunday, May 4, 2025. (AP Photo/Manuel Balce Ceneta)
The hot-button issue of uranium enrichment has plagued talks with Iran over the last few decades. The Europeans faced intense criticism when they agreed—independent of the U.S.—to allow the Islamic Republic to enrich uranium during the nascent phase of atomic talks during the early years of this century.
Brodsky said “The original sin of U.S. decision-making on Iran’s nuclear program was when the Obama administration changed the U.S. position from zero enrichment to tolerating enrichment at 3.67%. That laid the groundwork for Iran to retain the capability to continue to use its nuclear program to extort the United States and ultimately build a nuclear weapon.”
The nuclear expert noted, “That should end today, and recent comments from President Trump, Special Envoy Witkoff, and Secretary Rubio hopefully signal that this era is over. House and Senate Republicans were also very clear on this point over the last week. The Iranians say they want a durable deal. But a JCPOA 2.0—tolerating enrichment at 3.67% and no dismantlement of nuclear facilities—would not be one.
“The Iranians are engaged in all kinds of gimmicks to dress up a variation of the same concessions they offered to President Obama. That should be unacceptable to American negotiators.”
An Iranian military truck carries surface-to-air missiles past a portrait of Iran’s Supreme Leader Ayatollah Ali Khamenei during a parade on the occasion of the country’s annual army day on April 18, 2018 in Tehran, Iran. (ATTA KENARE/AFP via Getty Images)
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The anti-American news outlet, Kayhan, that serves as the mouthpiece for Khamenei, published a full-page screed against Trump where it stated, “He is a framework based on narcissism, superiority delusions, and threat-based tactics.”
The talks on Sunday ran for some three hours in Muscat, the capital of Oman. Iran’s regime spokesperson, Baghaei, said that a decision on the next round of talks is under discussion.
The Associated Press contributed to this report.
